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ARISE-HF is a study by Applied Therapeutics that investigates their Aldose Reductase Inhibitor, AT-001’s ability to improve or prevent the decline of functional capacity in patients with Diabetic Cardiomyopathy at high risk of progression to overt heart failure. After a brief discovery phase with account managers and the development team, we composed a site map, and then the subsequent wireframe. Adhering closely to Applied Therapeutics’ existing brand guidelines for ARISE-HF, I then crafted the visual design, which went through several iterations before the final version.